Covered on State Medicaid in 22 states:
* with a prior authorization
† on the Contracted Drug List for pediatric patients
Only with Siklos® can you get the benefits of:
It is not known if Siklos® is safe and effective in children less than 2 years.
WHAT IS THE MOST IMPORTANT INFORMATION YOU SHOULD KNOW ABOUT Siklos®?
Hydroxyurea is a medicine that can reduce:
Due to its benefits, hydroxyurea is considered the "gold standard" treatment for sickle cell disease.
Siklos® helps keep red blood cells round and flexible so they can travel more easily through blood vessels. Exactly how Siklos®produces its beneficial effects in patients is uncertain.
The result is that Siklos® may reduce painful crises and other complications of SCD.
Does your child struggle with taking compounded hydroxyurea (HU) medication? Insurance no longer covering compounded prescription medicines?
Siklos® is the ONLY dissolvable hydroxyurea medication.
Do you struggle with taking your HU capsules?
Siklos® is the ONLY hydroxyurea medication that comes in a 1,000 mg strengths tablet and is the ONLY breakable/dissolvable hydroxyurea medication.
Switch to Siklos® :
Talk with your doctor to see if Siklos® could be right for you or your child!
2 ways Siklos® can be taken:
It is important to take Siklos® once every day, at the same time each day, with a glass of water to get the most benefit from your hydroxyurea treatment.
View & print the Instructions for Taking Siklos®
Siklos® tablets must be handled with care. Follow applicable special handling and disposal procedures.
Do not take Siklos® if you are allergic to hydroxyurea or any of the ingredients in Siklos®
Sickle Cell Anemia (SCA) is one of a group of inherited disorders known as sickle cell disease (SCD).
Sickle cell disease affects red blood cells.
Normal red blood cells are round and flexible and can move easily through blood vessels.
For people with SCD, their red blood cells become stiff and curved (or shaped like a “sickle”), causing these cells to stick to blood vessels and block blood flow.
The blockages can cause crippling pain and other complications that can lead to hospitalization.
Siklos® is covered in many State Medicaid programs and has expanded commercial coverage!
If you have commercial insurance, there are 2 easy ways to pay as little as $0* for a Siklos® prescription!
Medunik USA also offers savings programs for patients that do not have commercial insurance or if their commercial insurance does not cover Siklos®.
*See Terms and Conditions
IMPORTANT SAFETY INFORMATION
Low blood cell counts are common with SIKLOS, including low red blood cells, white blood cells, and platelets, and can be severe and life threatening. If your white blood cell count becomes very low, you are at increased risk for infection. Your healthcare provider will check your blood cell counts before and every 2 weeks during treatment with SIKLOS. Your healthcare provider may change your dose or tell you to stop taking SIKLOS if you have low blood cell counts. Tell your healthcare provider right away if you get any of the following symptoms: fever or chills; shortness of breath; body aches; unusual headache; feeling very tired; bleeding or unexplained bruising.
Cancer. Some people have developed cancer, such as leukemia and skin cancer, after taking SIKLOS for a long time. Your healthcare provider will check you for cancer. You should protect your skin from the sun using sunblock, hats, and sun-protective clothing.
WHAT IS THE MOST IMPORTANT INFORMATION YOU SHOULD KNOW ABOUT SIKLOS?
WHO SHOULD NOT TAKE SIKLOS
Do not take SIKLOS if you are allergic to hydroxyurea or any of the ingredients in SIKLOS. See the Medication Guide for a list of the ingredients in SIKLOS.
WHAT SHOULD YOU TELL YOUR HEALTH CARE PROVIDER BEFORE TAKING SIKLOS?
Tell your healthcare provider about all of your medical conditions, including if you:
WHAT ARE THE POSSIBLE SIDE EFFECTS OF SIKLOS?
SIKLOS may cause serious side effects, including:
See "What is the most important information I should know about SIKLOS"
The most common side effects of SIKLOS in children include: infections and low white blood cells.
The most common side effects of SIKLOS in adults include: infections, headache, and dry skin.
These are not all the possible side effects of SIKLOS.
You are encouraged to report negative side effects of prescription drugs to the FDA at fda.gov/medwatch, or 1-800-FDA-1088.
Please read the Full Prescribing Information, including Boxed Warning, Medication Guide and Instructions for Use, at SIKLOSusa.com.
SIKLOS is a prescription medicine that is used to reduce the frequency of painful crises and reduce the need for blood transfusions in adults and children, 2 years of age and older, with sickle cell anemia with recurrent moderate to severe painful crises. It is not known if SIKLOS is safe and effective in children less than 2 years of age.
IMPORTANT SAFETY INFORMATION
Low blood cell counts are common with SIKLOS, including low red blood cells, white blood cells, and platelets, and can be severe and life threatening. If your white blood cell count becomes very low, you are at increased risk for infection. Your healthcare provider will check your blood cell counts before and every 2 weeks during treatment with SIKLOS. Your healthcare provider may change your dose or tell you to stop taking SIKLOS if you have low blood cell counts. Tell your healthcare provider right away if you get any of the following symptoms: fever or chills; shortness of breath; body aches; unusual headache; feeling very tired; bleeding or unexplained bruising.
Cancer. Some people have developed cancer, such as leukemia and skin cancer, after taking SIKLOS for a long time. Your healthcare provider will check you for cancer. You should protect your skin from the sun using sunblock, hats, and sun-protective clothing.
SIKLOS is a prescription medicine that is used to reduce the frequency of painful crises and reduce the need for blood transfusions in adults and children, 2 years of age and older, with sickle cell anemia with recurrent moderate to severe painful crises. It is not known if SIKLOS is safe and effective in children less than 2 years of age.